vaccines and immunoinformatics approaches

Motivation: The identification of novel drug-target (DT) interactions is a substantial part of the drug discovery process. Most of the computational methods that have been proposed to predict DT interactions have focused on binary classification, where the goal is to determine whether a DT pair interacts or not. Howev…

• ARZUCAN ÖZGÜR TÜRKMEN

Drug repositioning is the process of identifying novel therapeutic potentials for existing drugs and discovering therapies for untreated diseases. Drug repositioning, therefore, plays an important role in optimizing the pre-clinical process of developing novel drugs by saving time and cost compared to the traditional…

Homology modeling is one of the computational structure prediction methods that are used to determine protein 3D structure from its amino acid sequence. It is considered to be the most accurate of the computational structure prediction methods. It consists of multiple steps that are straightforward and easy to apply.…

• MUHAMMED TILAHUN MUHAMMED

Background Pneumococcal conjugate vaccines have reduced the incidence of invasive pneumococcal disease, caused by vaccine serotypes, but non-vaccine-serotypes remain a concern. We used whole genome sequencing to study pneumococcal serotype, antibiotic resistance and invasiveness, in the context of genetic background.…

• ÖZGEN ESER

Abstract B cells are frequently found in the margins of solid tumours as organized follicles in ectopic lymphoid organs called tertiary lymphoid structures (TLS) 1,2 . Although TLS have been found to correlate with improved patient survival and response to immune checkpoint blockade (ICB), the underlying mechanisms of…

No abstract yet.

No abstract yet.

• SALİH GÜNEŞ

No abstract yet.

• HANİFE AYŞEGÜL MENDİ

No abstract yet.

• PELİN KILIÇ

No abstract yet.

• EVRİM GÜNEŞ ALTUNTAŞ

No abstract yet.

• DEVRİM DEMİR DORA
• EVRİM GÜNEŞ ALTUNTAŞ

No abstract yet.

• BENGÜ NİSA AKAY
• GÜLDANE CENGİZ SEVAL