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OpenAlex topic

Cancer therapeutics and mechanisms

This page lists works and academicians tagged with an OpenAlex topic. It is not a YÖKSİS primary or secondary field.

OpenAlex 2,022 works 40 author topics

Works

2,022 works

  1. Drug repurposing for coronavirus (COVID-19): in silico screening of known drugs against coronavirus 3CL hydrolase and protease enzymes 2021
    YÖKSİS SJR Q2 JCR Q1 OpenAlex top 1% OpenAlex 99.9%

    In December 2019, COVID-19 epidemic was described in Wuhan, China, and the infection has spread widely affecting hundreds of thousands. Herein, an effort was made to identify commercially available drugs in order to repurpose them against coronavirus by the means of structure-based virtual screening. In addition, ZINC…

  2. Efficacy and Safety of Rovalpituzumab Tesirine Compared With Topotecan as Second-Line Therapy in DLL3-High SCLC: Results From the Phase 3 TAHOE Study 2021
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 1% OpenAlex 99.5%

    Introduction DLL3, an atypical Notch ligand, is expressed in SCLC tumors but is not detectable in normal adult tissues. Rovalpituzumab tesirine (Rova-T) is an antibody-drug conjugate containing a DLL3-targeting antibody tethered to a cytotoxic agent pyrrolobenzodiazepine by means of a protease-cleavable linker. The ef…

  3. Luotonin A A Naturally Occurring Human DNA Topoisomerase I Poison 2003
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 10% OpenAlex 92.9%

    Luotonin A is a pyrroloquinazolinoquinoline alkaloid isolated from the Chinese herbal medicinal plant Peganum nigellastrum. Although previously shown to exhibit cytotoxicity against the murine leukemia P-388 cell line, the mechanism of action of luotonin A is unknown. Presently, we demonstrate that luotonin A stabiliz…

  4. Synthesis and structure–activity relationships of new antimicrobial active multisubstituted benzazole derivatives 2004
    OpenAlex top 10% OpenAlex 95.2%

    No abstract yet.

  5. Synthesis and biological activities of diflunisal hydrazide–hydrazones 2003
    OpenAlex 82.6%

    No abstract yet.

  6. Synthesis and biological activities of diflunisal hydrazide hydrazones 2003
    YÖKSİS SJR Q1 JCR Q2 OpenAlex 82.6%

    No abstract yet.

  7. Natural Products and Synthetic Analogs as a Source of Antitumor Drugs 2019
    YÖKSİS SJR Q1 JCR Q2 OpenAlex top 1% OpenAlex 99.5%

    Cancer is a heterogeneous disease and one of the major issues of health concern, especially for the public health system globally. Nature is a source of anticancer drugs with abundant pool of diverse chemicals and pharmacologically active compounds. In recent decade, some natural products and synthetic analogs have be…

  8. Synthesis and structure antituberculosis activity relationship of 1H indole 2 3 dione derivatives 2007
    YÖKSİS SJR Q1 JCR Q2 OpenAlex top 10% OpenAlex 94.0%

    New series of 5-fluoro-1H-indole-2,3-dione-3-thiosemicarbazones 2a-k and 5-fluoro-1-morpholino/piperidinomethyl-1H-indole-2,3-dione-3-thiosemicarbazones 3a-r were synthesized. The structures of the synthesized compounds were confirmed by spectral data, elemental and single crystal X-ray diffraction analysis. The new 5…

  9. Synthesis and structure antituberculosis activity relationship of 1H indole 2 3 dione derivatives 2007
    YÖKSİS SJR Q1 JCR Q2 OpenAlex top 10% OpenAlex 93.9%

    New series of 5-fluoro-1H-indole-2,3-dione-3-thiosemicarbazones 2a-k and 5-fluoro-1-morpholino/piperidinomethyl-1H-indole-2,3-dione-3-thiosemicarbazones 3a-r were synthesized. The structures of the synthesized compounds were confirmed by spectral data, elemental and single crystal X-ray diffraction analysis. The new 5…

  10. Synthesis and structure antituberculosis activity relationship of 1H indole 2 3 dione derivatives 2007
    YÖKSİS SJR Q1 JCR Q2 OpenAlex top 10% OpenAlex 94.0%

    New series of 5-fluoro-1H-indole-2,3-dione-3-thiosemicarbazones 2a-k and 5-fluoro-1-morpholino/piperidinomethyl-1H-indole-2,3-dione-3-thiosemicarbazones 3a-r were synthesized. The structures of the synthesized compounds were confirmed by spectral data, elemental and single crystal X-ray diffraction analysis. The new 5…

  11. Synthesis and antimycobacterial activity of some coupling products from 4 aminobenzoic acid hydrazones 1999
    YÖKSİS SJR Q1 JCR Q3 OpenAlex 88.9%

    No abstract yet.

  12. Synthesis and antimycobacterial activity of some coupling products from 4 aminobenzoic acid hydrazones 1999
    YÖKSİS SJR Q1 JCR Q3 OpenAlex 88.9%

    No abstract yet.

Academicians

40 academicians