OpenAlex 1,155 works 36 author topics
Works
1,155 works
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Among the TRPC subfamily of TRP (classical transient receptor potential) channels, TRPC3, -6, and -7 are gated by signal transduction pathways that activate C-type phospholipases as well as by direct exposure to diacylglycerols. Since TRPC6 is highly expressed in pulmonary and vascular smooth muscle cells, it represen…
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New Molecular Mechanisms on the Activation of TRPM2 Channels by Oxidative Stress and ADP-Ribose 2007OpenAlex top 10% OpenAlex 96.8%
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The TRPC (C-type transient receptor potential) class of ion channels has been hypothesized to participate in store-operated Ca(2+) entry (SOCE). Recently, however, STIM1 and Orai1 proteins have been proposed to form SOCE channels. Whether TRPCs participate in SOCE that is dependent on or regulated by Orai has not been…
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OpenAlex 88.7%
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OpenAlex 85.4%
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BACKGROUND: Catalase catalyzes the reduction of H(2)O(2) to water and it can also remove organic hydroperoxides. Nervous system in body is especially sensitive to free radical damage due to rich content of easily oxidizible fatty acids and relatively low content of antioxidants including catalase. Recent studies indic…
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1.5 expression as a new underlying molecular mechanism. Taken together, these findings broaden our understanding of the genetic architecture of BrS and provide new insights into its molecular underpinnings.
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Cancer is one of the most fatal diseases with an increasing incidence and mortality all over the world. Thus, there is an urgent need for novel therapies targeting major cancer-related pathways. Nuclear factor-erythroid 2-related factor 2 (NRF2) and its major negative modulator Kelch-like ECH-associated protein 1 (KEA…
Academicians
36 academicians
- MUSTAFA NAZIROĞLU 114 author topics
- İSHAK SUAT ÖVEY 29 author topics
- KENAN YILDIZHAN 26 author topics
- RAMAZAN ÇINAR 14 author topics
- ŞERİFE TÜTÜNCÜ 12 author topics
- YASEMİN ERAÇ 12 author topics
- EDA YILDIRIM 11 author topics
- MURAT ÇAKIR 11 author topics
- KEMAL ERTİLAV 9 author topics
- RAMAZAN BAL 9 author topics
- SERDAR ÖZTUZCU 9 author topics
- ÖMER ÇELİK 8 author topics