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OpenAlex topic

Telomeres, Telomerase, and Senescence

This page lists works and academicians tagged with an OpenAlex topic. It is not a YÖKSİS primary or secondary field.

OpenAlex 777 works 15 author topics

Works

777 works

  1. Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses 2016
    YÖKSİS SJR Q1 JCR Q2 OpenAlex top 1% OpenAlex 99.1%

    Senescent cells secrete senescence-associated secretory phenotype (SASP) proteins to carry out several functions, such as sensitizing surrounding cells to senesce; immunomodulation; impairing or fostering cancer growth; and promoting tissue development. Identifying secreted factors that achieve such tasks is a challen…

  2. Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses 2016
    OpenAlex top 1% OpenAlex 99.0%

    Senescent cells secrete senescence-associated secretory phenotype (SASP) proteins to carry out several functions, such as sensitizing surrounding cells to senesce; immunomodulation; impairing or fostering cancer growth; and promoting tissue development. Identifying secreted factors that achieve such tasks is a challen…

  3. Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses 2016
    YÖKSİS SJR Q1 JCR Q2 OpenAlex top 1% OpenAlex 99.0%

    Senescent cells secrete senescence-associated secretory phenotype (SASP) proteins to carry out several functions, such as sensitizing surrounding cells to senesce; immunomodulation; impairing or fostering cancer growth; and promoting tissue development. Identifying secreted factors that achieve such tasks is a challen…

  4. Transforming growth factor beta induces senescence in hepatocellular carcinoma cells and inhibits tumor growth 2010
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 10% OpenAlex 97.1%

    UNLABELLED: Senescence induction could be used as an effective treatment for hepatocellular carcinoma (HCC). However, major senescence inducers (p53 and p16(Ink4a)) are frequently inactivated in these cancers. We tested whether transforming growth factor-beta (TGF-beta) could serve as a potential senescence inducer in…

  5. Transforming growth factor beta induces senescence in hepatocellular carcinoma cells and inhibits tumor growth 2010
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 10% OpenAlex 97.2%

    UNLABELLED: Senescence induction could be used as an effective treatment for hepatocellular carcinoma (HCC). However, major senescence inducers (p53 and p16(Ink4a)) are frequently inactivated in these cancers. We tested whether transforming growth factor-beta (TGF-beta) could serve as a potential senescence inducer in…

  6. Transforming growth factor beta induces senescence in hepatocellular carcinoma cells and inhibits tumor growth 2010
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 10% OpenAlex 97.1%

    UNLABELLED: Senescence induction could be used as an effective treatment for hepatocellular carcinoma (HCC). However, major senescence inducers (p53 and p16(Ink4a)) are frequently inactivated in these cancers. We tested whether transforming growth factor-beta (TGF-beta) could serve as a potential senescence inducer in…

  7. GWAS of epigenetic aging rates in blood reveals a critical role for TERT 2018
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 1% OpenAlex 99.2%

    Abstract DNA methylation age is an accurate biomarker of chronological age and predicts lifespan, but its underlying molecular mechanisms are unknown. In this genome-wide association study of 9907 individuals, we find gene variants mapping to five loci associated with intrinsic epigenetic age acceleration (IEAA) and g…

  8. The cell fate: senescence or quiescence 2016
    YÖKSİS SJR Q2 JCR Q4 OpenAlex top 10% OpenAlex 98.9%

    No abstract yet.

  9. The cell fate: senescence or quiescence 2016
    YÖKSİS SJR Q2 JCR Q4 OpenAlex top 10% OpenAlex 98.9%

    No abstract yet.

  10. Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk 2014
    OpenAlex top 1% OpenAlex 99.3%

    No abstract yet.

  11. Continuous elimination of oxidized nucleotides is necessary to preventrapid onset of cellular senescence 2009
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 10% OpenAlex 96.6%

    Reactive oxygen species (ROS) appear to play a role in limiting both cellular and organismic lifespan. However, because of their pleiotropic effects, it has been difficult to ascribe a specific role to ROS in initiating the process of cellular senescence. We have studied the effects of oxidative DNA damage on cell pro…

  12. Continuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence 2009
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 10% OpenAlex 96.6%

    Reactive oxygen species (ROS) appear to play a role in limiting both cellular and organismic lifespan. However, because of their pleiotropic effects, it has been difficult to ascribe a specific role to ROS in initiating the process of cellular senescence. We have studied the effects of oxidative DNA damage on cell pro…

Academicians

15 academicians