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OpenAlex topic

Wnt/β-catenin signaling in development and cancer

This page lists works and academicians tagged with an OpenAlex topic. It is not a YÖKSİS primary or secondary field.

OpenAlex 991 works 16 author topics

Works

991 works

  1. EMT, the cytoskeleton, and cancer cell invasion 2009
    SJR Q1 JCR Q1 OpenAlex top 1% OpenAlex 99.9%

    No abstract yet.

  2. Loss of E cadherin promotes metastasis via multiple downstreamtranscriptional pathways 2008
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 1% OpenAlex 99.8%

    Loss of the epithelial adhesion molecule E-cadherin is thought to enable metastasis by disrupting intercellular contacts-an early step in metastatic dissemination. To further investigate the molecular basis of this notion, we use two methods to inhibit E-cadherin function that distinguish between E-cadherin's cell-cel…

  3. Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways 2008
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 1% OpenAlex 99.8%

    Loss of the epithelial adhesion molecule E-cadherin is thought to enable metastasis by disrupting intercellular contacts-an early step in metastatic dissemination. To further investigate the molecular basis of this notion, we use two methods to inhibit E-cadherin function that distinguish between E-cadherin's cell-cel…

  4. β-Catenin Regulates the Expression of the Matrix Metalloproteinase-7 in Human Colorectal Cancer 1999
    OpenAlex top 1% OpenAlex 99.7%

    No abstract yet.

  5. GLI1-expressing mesenchymal cells form the essential Wnt-secreting niche for colon stem cells 2018
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 1% OpenAlex 99.5%

    No abstract yet.

  6. A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma 2017
    OpenAlex top 1% OpenAlex 99.4%

    No abstract yet.

  7. Mouse Model of Colonic Adenoma Carcinoma Progression Based on Somatic Apc Inactivation 2007
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 10% OpenAlex 95.6%

    Mutations in the adenomatous polyposis coli (APC) gene are pivotal in colorectal tumorigenesis. Existing mouse intestinal tumor models display mainly small intestinal lesions and carcinomas are rare. We defined human CDX2 sequences conferring colon epithelium-preferential transgene expression in the adult mouse. Mice…

  8. c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism. 1995

    We have explored the role of the tyrosine kinase c-Src in cellular adhesion. Fibroblasts derived from src-/- mice (src-/- fibroblasts) exhibit a reduced rate of spreading on fibronectin. These defect is rescued by expression of wild-type chicken c-Src. Analyses of mutants suggest that c-Src increases the rate of cell…

  9. Mouse Model of Human Ovarian Endometrioid Adenocarcinoma Based on Somatic Defects in the Wnt Catenin and PI3K Pten Signaling Pathways 2007
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 10% OpenAlex 98.6%

    No abstract yet.

  10. beta Catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N Ras in melanoma development 2007
    YÖKSİS SJR Q1 JCR Q1

    Tumor progression is a multistep process in which proproliferation mutations must be accompanied by suppression of senescence. In melanoma, proproliferative signals are provided by activating mutations in NRAS and BRAF, whereas senescence is bypassed by inactivation of the p16(Ink4a) gene. Melanomas also frequently ex…

  11. Recessive Robinow syndrome allelic to dominant brachydactyly type B is caused by mutation of ROR2 2000
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 10% OpenAlex 93.5%

    No abstract yet.

  12. Mutations in WNT1 cause different forms of bone fragility 2013 Apr 4 92 4 565 74 doi Epub 2013 Mar 14 2013
    YÖKSİS SJR Q1 JCR Q1 OpenAlex top 1% OpenAlex 99.6%

    No abstract yet.

Academicians

16 academicians