Horizon Europe · Horizon Europe (HORIZON)
Development of cell-free protein synthesis platforms for discovery and/or production of biologicals
Call summary
From the official text, opening part
Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Maintaining an innovative, sustainable, and competitive EU health industry”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes: Biopharmaceutical industries get access to streamlined development and production processes for peptide- or protein-based biologicals. Health systems benefit from the availability of enhanced or decentralised production systems for innovative health technologies that involve peptides or proteins, and which improve health and care. Citizens and patients will benefit from better access, availability and affordability of pharmaceuticals based on biologicals. Scope: Cell-Free Protein Synthesis (CFPS) has been em… more
Basic medicineBasic pharmacologyHealth-related biotechnologyMedical biotechnologyPharmaceutical developmentcell-freeprotein synthesis
Academics who may be relevant
By subject fit
30-
%59SERVET TUNOĞLU
Shared topics: Computational Drug Discovery Methods · Protein Structure and Dynamics · Nanoparticles: synthesis and applications
Overlapping papers: Epigenetic Signatures in Ovarian Cancer to Determine Potential Diagnostic/Prognostic Biomarkers (2024) · Gene Expression Levels Related To Histone Acetylation Are Altered In PD Patients (2024)
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%58AYSUN YÜCETEPE
Shared topics: Proteins in Food Systems · Protein Hydrolysis and Bioactive Peptides · Algal biology and biofuel production
Overlapping papers: Millet Proteins Beyond Nutrition: Functional, Structural and Engineering Attributes (2026) · Exploring the Uncharted Potential of Sea Plants for Diabetes Management: Advances, Challenges, and Future Directions (2026)
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%56ALPEREN CANPOLAT
Shared topics: Protein Hydrolysis and Bioactive Peptides
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%56EZGİ NURDAN YENİLMEZ TUNOĞLU
Shared topics: Computational Drug Discovery Methods · Synthesis and biological activity · Heat shock proteins research
Overlapping papers: Design, Synthesis, and Evaluation of Benzimidazole‐Carbazole Hybrids Targeting Heat Shock Proteins‐Mediated Apoptosis in Breast and Colon Cancer Cells (2025) · A potential posttranscriptional regulator for p60-katanin: miR- 124-3p (2023)
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%55BETÜL KAYA
Shared topics: Synthesis and biological activity · Synthesis and Biological Evaluation · Computational Drug Discovery Methods
Overlapping papers: Synthesis and characterization of a new series of thiadiazole derivatives as potential anticancer agents (2020) · Design, Synthesis, Biological Evaluation, and Molecular Docking Studies of Novel 1,3,4-Thiadiazole Derivatives Targeting Both Aldose Reductase and α-Glucosidase for Diabetes Mellitus (2025)
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%55ERSİN DEMİR
Shared topics: Synthesis and biological activity · Synthesis and properties of polymers
Overlapping papers: Synthesis, Structural Characterization, and Thermal Stability Investigation of Methoxybenzamide Derivatives Containing the 5-Mercapto-1,3,4-Thiadiazol-2-yl Group (2025) · Synthesis, spectral characterization and biological activities of o,o-dihydroxyazo compounds containing gallic acid: Molecular docking and dynamics simulation and MM-PBSA studies (2024)
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%54HASAN UFUK ÇELEBİOĞLU
Shared topics: Microbial Metabolites in Food Biotechnology · Nanoparticles: synthesis and applications · Protein Hydrolysis and Bioactive Peptides
Overlapping papers: Differential proteome and cellular adhesion analyses of the probiotic bacterium Lactobacillus acidophilus NCFM grown on raffinose - an emerging prebiotic (2016) · Cytotoxic Effects of Probiotic Bacteria Lactobacillus acidophilus and Lactobacillus rhamnosus Grown in the Presence of Oleuropein on Human Prostate Cancer Cells (2020)
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%53AYŞE ÖZDEMİR
Shared topics: Metal complexes synthesis and properties · Protein Interaction Studies and Fluorescence Analysis
Overlapping papers: Investigation of binding properties of dicationic styrylimidazo[1,2-a]pyridinium dyes to human serum albumin by spectroscopic techniques (2017) · Investigation of binding properties of dicationic styrylimidazo[1,2-a]pyridinium dyes to human serum albumin by spectroscopic techniques (2017)
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%53DENİZ AKTAŞ UYGUN
Shared topics: Protein purification and stability
Overlapping papers: DNA isolation by galactoacrylate-based nano-poly(HEMA-co-Gal-OPA) nanopolymers (2017) · Boronate affinity nanoparticles for nucleoside separation (2016)
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%53SEDA ARICI
Shared topics: Hydrogels: synthesis, properties, applications · Advanced Polymer Synthesis and Characterization
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%53ÖZLEM KAPLAN
Shared topics: Nanoparticles: synthesis and applications · Heat shock proteins research
Overlapping papers: Escherichia coli in the production of biopharmaceuticals (2025) · Green synthesized silver nanoparticles with mushroom extracts of Paxina leucomelas and Rhizopogon luteolus induce ROS-Induced intrinsic apoptotic pathway in cancer cells (2024)
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%52BEDİA KAYMAKÇIOĞLU
Shared topics: Synthesis and biological activity · Computational Drug Discovery Methods · Synthesis and Characterization of Heterocyclic Compounds
Overlapping papers: Design, synthesis, biological evaluation and molecular docking of novel moleculesto PARP-1 enzyme (2019) · Synthesis and Biological Evaluation of Some Hydrazide-Hydrazone Derivatives as Anticancer Agents (2022)
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%52CANAN ÇAKIR
Shared topics: Computational Drug Discovery Methods · Synthesis and biological activity · Pharmacological Effects of Natural Compounds · Synthesis and Biological Evaluation
Overlapping papers: Preclinical toxicity test results of a new antiviral–immune-modulator compound consisting of flavonoid molecules (COVID-19 clinical trial preliminary data) (2022) · Acquiring stereospecific new pseudosugars: Obtaining rac-decahydro-1,4-epoxynaphthalene-2,3,5,6,7,8-hexaols from the Diels-Alder reaction and investigating their biological effects (2025)
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%51ÖZKAN FİDAN
Shared topics: Microbial Natural Products and Biosynthesis · Mesenchymal stem cell research · Pharmacological Effects of Natural Compounds
Overlapping papers: Engineered production of bioactive natural products from medicinal plants (2022) · Recent advances in engineering yeast for pharmaceutical protein production (2015)
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%50CANSU YAY
Shared topics: Proteins in Food Systems · Protein Hydrolysis and Bioactive Peptides
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%50ZAFER AYDIN
Shared topics: Protein Structure and Dynamics · Computational Drug Discovery Methods · RNA and protein synthesis mechanisms
Overlapping papers: Using machine learning to speed up manual image annotation application to a 3D imaging protocol for measuring single cell gene expression in the developing C elegans embryo (2010) · Learning sparse models for a dynamic Bayesian network classifier of protein secondary structure (2011)
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%49AHMET KARAKUŞ
Shared topics: Computational Drug Discovery Methods · Mesenchymal stem cell research · Synthesis and biological activity
Overlapping papers: 5,7,8-trihydroxyflavone Has Anticancer and Apoptotic Effects in Human Androgen-Independet Prostate Cancer PC-3 Cells (2023) · Cloning and Expression of Rat Brain Acetylcholinesterase Enzyme in Escherichia coli (2022)
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%49AYSUN ÖZDEMİR
Shared topics: Protein Kinase Regulation and GTPase Signaling · Cell death mechanisms and regulation · Synthesis and biological activity
Overlapping papers: Synthesis and molecular modeling of some novel hydroxypyrone derivatives as antidermatophytic agents (2022) · Antimigratory effect of pyrazole derivatives through the induction of STAT1 phosphorylation in A549 cancer cells (2021)
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%49BİLGE ÇİFTCİ
Shared topics: Computational Drug Discovery Methods · Synthesis and biological activity
Overlapping papers: Design, Synthesis, Biological Evaluation, and Molecular Docking Studies of Novel 1,3,4-Thiadiazole Derivatives Targeting Both Aldose Reductase and α-Glucosidase for Diabetes Mellitus (2025) · Design, Synthesis, In Silico Absorption, Distribution, Metabolism, and Elimination and Molecular Docking Studies of Thiazole‐Based Furan Derivatives, and Their Biological Evaluation for Alzheimer Disease Therapy (2025)
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%49HALİL BARIŞ ÖZEL
Shared topics: Proteins in Food Systems · Meat and Animal Product Quality
Overlapping papers: Adsorption property and mechanism of forest wastes based naturel adsorbent for removal of dye from aqueous media (2023) · Determining the taxol contents of yew tree populations in western Black Sea and Marmara regions and analyzing some forest stand characteristics (2023)
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%49HANDE KAZAK SARILMIŞER
Shared topics: Microbial Metabolites in Food Biotechnology · Enzyme Production and Characterization
Overlapping papers: Levan-based nanocarrier system for peptide and protein drug delivery:Optimization and influence of experimental parameters on thenanoparticle characteristics (2011) · Development and characterization of vancomycin-loaded levan-based microparticular system for drug delivery. (2017)
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%49RİZVAN İMAMOĞLU
Shared topics: Nanoparticles: synthesis and applications · Computational Drug Discovery Methods · Synthesis and biological activity
Overlapping papers: Synthesis of silver nanowires in a two\u2010phase system for biological applications (2021) · Green synthesized silver nanoparticles with mushroom extracts of Paxina leucomelas and Rhizopogon luteolus induce ROS-Induced intrinsic apoptotic pathway in cancer cells (2024)
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%49YAHYA YASİN YILMAZ
Shared topics: Bee Products Chemical Analysis · Protein Hydrolysis and Bioactive Peptides · Proteins in Food Systems
Overlapping papers: ARI ZEHRİ VE MELLİTİN PEPTİDİNİN ANTİKANSER ÖZELLİKLERİNİN İNCELENMESİ (2024)
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%48AHMET ÇAĞRI KARABURUN
Shared topics: Synthesis and biological activity · Multicomponent Synthesis of Heterocycles · Synthesis and Characterization of Heterocyclic Compounds · Computational Drug Discovery Methods
Overlapping papers: Design, synthesis, biological evaluation, and molecular modeling simulations of new phthalazine-1,4-dione derivatives as anti-Alzheimer's agents (2024) · Computational insights into the chemical reactivity of Alzheimer’s therapeutics: a DFT-based study (2025)
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%48BEYZANUR TUTUŞ
Shared topics: Synthesis and biological activity · Computational Drug Discovery Methods · Advanced Polymer Synthesis and Characterization · Pharmaceutical Practices and Patient Outcomes
Overlapping papers: Synthesis of Quinazoline Derivatives and Mechanistic Approaches in Lung and Breast Cancers (2026) · Synthesis of new N‐(5,6‐methylenedioxybenzothiazole‐2‐yl)‐2‐[(substituted)thio/piperazine]acetamide/propanamide derivatives and evaluation of their AChE, BChE, and BACE‐1 inhibitory activities (2024)
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%48GÜLEN MELİKE DEMİRBOLAT
Shared topics: Nanoparticles: synthesis and applications · Cell death mechanisms and regulation
Overlapping papers: TRAIL-PEG-Apt-PLGA nanosystem as an aptamer-targeted drug delivery system potential for triple-negative breast cancer therapy using in vivo mouse model (2026) · Wharton jelly-derived mesenchymal stem cell exosomes induce apoptosis and suppress EMT signaling in cervical cancer cells as an effective drug carrier system of paclitaxel. (2022)
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%47ABDULİLAH ECE
Shared topics: Synthesis and biological activity · Computational Drug Discovery Methods · Phenothiazines and Benzothiazines Synthesis and Activities
Overlapping papers: Synthesis, Biological Evaluation and in Silico Studies of Novel Urea/Thiourea Derivatives of Lenalidomide (2024) · Towards more effective acetylcholinesterase inhibitors: a comprehensive modelling study based on human acetylcholinesterase protein–drug complex (2019)
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%47AYKUT ÖZTEKİN
Shared topics: Synthesis and biological activity · Nanoparticles: synthesis and applications
Overlapping papers: In vitro Inhibition Profiles and Molecular Docking Analysis of Benzohydrazide Derivatives on Red Blood Cell Carbonic Anhydrases Isozymes (2022) · Synthesis and biological evaluation of novel salicylidene uracils: Cytotoxic activity on human cancer cell lines and inhibitory action on enzymatic activity (2024)
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%47AYLİN AKOĞLU
Shared topics: Meat and Animal Product Quality · Protein Hydrolysis and Bioactive Peptides
Overlapping papers: Control of Listeria monocytogenes biofilm on industrial surfaces by cell‐free extracts of Lactobacillus plantarum (2021) · Bıldırcın Nugget Üretimi ve Depolama Stabilitesinin Belirlenmesi (2019)
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%47AYŞE SELEN ALP
Shared topics: Synthesis and biological activity · Computational Drug Discovery Methods · Quinazolinone synthesis and applications · Protein Structure and Dynamics
Overlapping papers: Inhibitory effects of indole lipoic acid derivatives on nitric oxide production in LPS IFN activated RAW 264 7 macrophages (2015) · Novel indole retinoid derivative induces apoptosis and cell cycle arrest and modulates AKT and ERK signaling in HL‐60 cells (2023)
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