Evaluation of Individual Dependence and Reproducibility of Central Corneal Thickness Measurements with Anterior Segment Optical Coherence Tomography

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Abstract Aim: To compare corneal thickness measurements made at different times and to evaluate their dependence on individuals. Materials and Methods: The central corneal thickness of the right eyes of 30 healthy young adults was measured by the first investigator at three different times by the Anterior Segment Optical Coherence Tomography (AS-OCT) method. In addition, the fourth measurements were made by the second researcher at a different time. The obtained values were compared. Results: The mean age was 29.8 ± 9.1 years. The mean CCT was 561.90 ± 37.6 µ in the first measurement, 562.20 ± 37.9 µ in the second measurement, and 562.80 ± 37.7 µ in the third measurement. In the measurement of CCT by the second investigator, the mean was 562.20 ± 38.0 µ. In statistical analysis, no significant difference was found between CCT values performed at different times (p<0.05). In addition, when the first measurement of the first researcher was compared with the first measurement of the second researcher, no significant difference was found between the CCT values of the two researchers (p<0.05). Conclusion: Canon HS-100 AS-OCT device had very good reproducibility in the evaluation of CCT. There was no significant difference between the shots of different people. The use of OCT in daily practice is beneficial because it is both a non-contact method and has very good reproducibility in daily practice. Keywords: Central corneal thickness, reproducibility, measurement