Cancer and biochemical research

BACKGROUND: The proto-oncogene bcl-2 encodes a protein that inhibits programmed cell death (apoptosis). The protein is expressed in basal cells in normal human epithelium, but no data are available on the frequency or clinical importance of its expression in carcinoma. We studied bcl-2 expression in patients with non-…

• IŞINSU KUZU

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• AHMET BELCE

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• AYLİN YÜCEL

BACKGROUND: Regulation of cell size requires coordination of growth and proliferation. Conditional loss of cyclin-dependent kinase 1 in mice permits hepatocyte growth without cell division, allowing us to study cell size in vivo using transcriptomics and metabolomics. RESULTS: Larger cells displayed increased expressi…

• MUHAMMED KASIM DİRİL

In this study, removal of some heavy metals ions (Mn2+, Fe2+, Ni2+ and Cu2+) from aqueous solution by adsorption was investigated. For this purpose, high-grade MnSO4.H2O, FeSO4.7H2O, NiSO4.7H2O and CuSO4.5H2O were used as heavy metal samples. The commercial activated carbon (Merck 2514), chitosan and agar were used as…

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• AYŞE EKEN

Peroxidases (EC 1.11.1.7; donor: hydrogen peroxide oxidoreductase) are part of a large group of enzymes. In this study, peroxidase, a primer antioxidant enzyme, was purified with 19.3 fold and 0.2% efficiency from cauliflower (Brassica oleracea L.) by ammonium sulphate precipitation, dialysis, CM-Sephadex ion-exchange…

• EKREM KÖKSAL

Peroxidases (EC 1.11.1.7; donor: hydrogen peroxide oxidoreductase) are part of a large group of enzymes. In this study, peroxidase, a primer antioxidant enzyme, was purified with 19.3 fold and 0.2% efficiency from cauliflower (Brassica oleracea L.) by ammonium sulphate precipitation, dialysis, CM-Sephadex ion-exchange…

• İLHAMİ GÜLÇİN

BACKGROUND: One of the major goals of oncology is to predict the response of patients with cancer to chemotherapeutic agents by employing laboratory methods variously called 'tumor chemosensitivity assays', 'drug response assays', or 'drug sensitivity assays', in vitro. The MTT assay is one of the methods used to pred…

• ENGİN ULUKAYA

BACKGROUND: One of the major goals of oncology is to predict the response of patients with cancer to chemotherapeutic agents by employing laboratory methods variously called 'tumor chemosensitivity assays', 'drug response assays', or 'drug sensitivity assays', in vitro. The MTT assay is one of the methods used to pred…

• MUKADDES ÇOLAKOĞULLARI

The aim of this study was to investigate the alterations in lipid peroxidation and antioxidant enzyme defences in the blood of patients with malignant breast tumour and benign breast disease. Forty patients with malignant breast tumour, 20 patients with benign breast disease and also 20 healthy control subjects were r…

• FAZLI ERDOĞAN

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• TAHSİN ERMAN