Anesthesia and Neurotoxicity Research

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• FATİH ŞEN

Recent evidence suggests that neural stem/precursor cells (NPCs) promote recovery in animal models with delayed neuronal death via a number of indirect bystander effects. A comprehensive knowledge of how transplanted NPCs exert their therapeutic effects is still lacking. Here, we investigated the effects of a delayed…

BACKGROUND: Dexmedetomidine has shown sedative, analgesic, and anxiolytic effects after intravenous (IV) administration. Sevoflurane is associated with a high incidence of emergence agitation in preschool children. In this placebo-controlled study, we examined the effect of single dose dexmedetomidine on emergence agi…

• ZEYNEP TOSUN

In Brief We compared the sedative, hemodynamic, and respiratory effects of dexmedetomidine and propofol in children undergoing magnetic resonance imaging procedures. Sixty children were randomly distributed into two groups: The dexmedetomidine (D) group received 1 μg/kg initial dose followed by continuous infusion of…

In Brief We compared the sedative, hemodynamic, and respiratory effects of dexmedetomidine and propofol in children undergoing magnetic resonance imaging procedures. Sixty children were randomly distributed into two groups: The dexmedetomidine (D) group received 1 μg/kg initial dose followed by continuous infusion of…

• HÜSEYİN İLKSEN TOPRAK

BACKGROUND: Dexmedetomidine has shown sedative, analgesic, and anxiolytic effects after intravenous (IV) administration. Sevoflurane is associated with a high incidence of emergence agitation in preschool children. In this placebo-controlled study, we examined the effect of single dose dexmedetomidine on emergence agi…

• ALİYE ÇORUH

Previously it has been shown that ischemic preconditioning could increase the tolerance of intestinal tissue to ischemia [ 1 ]. In this study we investigated the effects of pharmacological preconditioning with adenosine infusion on intestinal ischemia/reperfusion (I/R) injury and bacterial translocation. We also evalu…

• CANDAN ÖZTÜRK
• NURCAN DORUK

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BACKGROUND: The purpose of the present study was to determine whether prophylactic use of 1 microg x kg(-1) dexmedetomidine affected the incidence of emergence agitation (EA) after sevoflurane based anesthesia without surgery in children. METHODS: In a double-blinded trial, 42 children (ASA I-II,18 months to 10 years)…

• ÖMER KURTİPEK

BACKGROUND: The purpose of the present study was to determine whether prophylactic use of 1 microg x kg(-1) dexmedetomidine affected the incidence of emergence agitation (EA) after sevoflurane based anesthesia without surgery in children. METHODS: In a double-blinded trial, 42 children (ASA I-II,18 months to 10 years)…

• BERRİN IŞIK

BACKGROUND: Neonates and infants requiring anaesthesia are at risk of physiological instability and complications, but triggers for peri-anaesthetic interventions and associations with subsequent outcome are unknown. METHODS: This prospective, observational study recruited patients up to 60 weeks' postmenstrual age un…

• PELİN ÇORMAN DİNÇER

BACKGROUND: Neonates and infants requiring anaesthesia are at risk of physiological instability and complications, but triggers for peri-anaesthetic interventions and associations with subsequent outcome are unknown. METHODS: This prospective, observational study recruited patients up to 60 weeks' postmenstrual age un…

• HALE AKSU