Gene Regulatory Network Analysis

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Genomic data allow the large-scale manual or semi-automated assembly of metabolic network reconstructions, which provide highly curated organism-specific knowledge bases. Although several genome-scale network reconstructions describe Saccharomyces cerevisiae metabolism, they differ in scope and content, and use differ…

• KAZIM YALÇIN ARGA

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In the Molecular Communication (MC), molecules are utilized to encode, transmit, and receive information. Transmission of the information is achieved by means of diffusion of molecules and the information is recovered based on the molecule concentration variations at the receiver location. The MC is very prone to inte…

• ÖZGÜR BARIŞ AKAN

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The latest advances in high-throughput techniques during the past decade allowed the systems biology field to expand significantly. Today, the focus of biologists has shifted from the study of individual biological components to the study of complex biological systems and their dynamics at a larger scale. Through the…

• ATHANASIA PAVLOPOULOU

In this study, we develop a new dynamical model of cancer growth, which includes the interactions between tumour cells, healthy tissue cells, and activated immune system cells, clearly leading to chaotic behavior. We explain the biological relevance of our model and the ways in which it differs from the existing ones.…

• MEHMET İTİK

Cells rely on the precise action of proteins that detect and repair DNA damage. However, gene expression noise causes fluctuations in protein abundances that may compromise repair. For the Ada protein in Escherichia coli, which induces its own expression upon repairing DNA alkylation damage, we found that undamaged ce…

Bio-inspired networking techniques have been investigated since more than a decade. Findings in this field have fostered new developments in networking, especially in the most challenging domains such as handling large-scale networks, their dynamic nature, resource constraints, heterogeneity, unattended operation, and…

• ÖZGÜR BARIŞ AKAN